DynICP project: Innovative Intracranial Pressure and Volume Wave Monitoring System

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The need for a non-invasive ICP measurement technology

An estimated 25M EU citizens suffer from chronic headaches and over 12M have some form of dementia. Each year, between 3M and 4M suffer head injuries (up to 25% of whom require hospitalization), over 1M suffer strokes and over 100,000 suffer various brain tumours. Intracranial pressure (ICP) monitoring is crucial for surveillance of patients with dementia, chronic headache, hydrocephalus, head injury, stroke, brain tumours and other brain diseases as well as for diagnostic purposes to determine the optimum treatment and for monitoring of effects of treatment. However, all currently available options rely on invasive placement of ICP probe in the patient cerebral spinal fluid, thus reducing its use to the intensive care units or hospital wards. Consequently, less than 100,000 patients receive ICP monitoring in the EU each year.

Therefore, the aim of this project is to develop an advanced, portable prototype of a non-invasive intracranial dynamic pressure diagnosing and monitoring device:

  • The DynICP device consists of a wearable head gear capable of precise positioning of two ultrasonic transducers, software and hardware for dynamic ICP analysis and data communication;
  • This device can be used at hospitals, point of care as well as at home;
  • The  non-invasive breakthrough DynICP solution will allow over 40M patients in EU to benefit from the ICP monitoring- this is at least 400 times more than with current invasive ICP measurement technology;
  • Expected benefits for the EU include a higher quality of life for millions of chronic headache and dementia sufferers and possible reduction of mortality rates of thousands of head injury and stroke victims.

Consortium

The DynICP consortium consists of 7 partners from 3 different countries: Estonia, Lithuania and Norway.

KAUNO TECHNOLOGIJOS UNIVERSITETAS  (LITHUANIA)

Kauno Technologijos Universitetas (KTU) is well-known in the world for their research achievements in the fields of Ultrasound, Organic Chemistry, Environmental Protection, Mechatronics, System Dynamics, Biomedical Engineering, and Educology. They carry out successful international projects and contracts in cooperation with foreign companies as well as enjoy close links with entities of the Lithuanian industry. KTU is the frontrunner in higher education in Lithuania in terms of number and budget of the contracts to be carried out in cooperation with Lithuanian companies.

OSLO UNIVERSITY HOSPITAL HF (NORWAY)

Oslo University Hospital (OUS) is a highly specialised hospital in charge of extensive regional and local hospital assignments and the provision of high quality services for the citizens of health region south-east of Norway. The hospital also has a nationwide responsibility for a number of national and multi-regional assignments and has several national centres of competence. The hospital carries out advanced patient treatment, research and trial treatments, give advice and provide education on international levels. OUS is responsible for approximately 50 percent of all medical and healthcare research conducted at Norwegian hospitals and is a significant role player within the education of a large variety of health care personnel.

DPCOM AS (NORWAY)

dPCom AS is a Norwegian medical technology company established in 2001. It manufactures medical software for the analysis of pressure signals via Sensometrics Technology. This is a software component implementing an intelligent and automatic identification of the cardiac beat-induced single pressure waves, and artefact pressure waves. It provides increased quality control and retrieves the static and pulsatile ICP (intracranial pressure) and ABP (arterial blood pressure) parameters from the automatically identified pressure waves and provides more reliable diagnostic information to the physicians.

ARTEC DESIGN OÜ (ESTONIA)

Located in Tallinn,  Estonia, Artec Design conceptualises, designs and manufactures user-friendly electronics for the environmentally-aware millennium. As a multi-discipline product development company with a competence span covering wireless technologies, data security, networking interfaces and various CPU hardware platforms, Artec’s team focuses on development and manufacturing of mobile and remote devices for embedded application,  integration and customization of software and hardware products to comply to market specific needs and customers’ requirements.

EESTI INNOVATSIOONI INSTITUUT OÜ (ESTONIA)

Eesti Innovatsiooni Instituut (EII), based in Estonia, Tallinn, is part of Pera Technology Ltd research institutes and knowledge transfer centres. With access to broad range of scientists, researchers and engineers, EII’s multi-disciplinary teams deliver R&D to industry across the Europe in the technological fields of ICT, medical devices, material science, manufacturing design and mechatronics. In addition to research capabilities, EII has highly qualified Research, Programme and Project Managers to make sure all RTD projects are delivered on time, customer expectations are exceeded and developed technologies meet preconditions needed for later commercial success. EII’s team has strong experience in international cooperation and development of partnering networks. To date EII has undertaken R&D delivery roles in more than 20 FP projects.
EII has currently 20 highly skilled employees in house which are complemented by 150 engineers and scientists through Pera Technology Ltd, whose fully owned subsidiary EII is, and has access to more than 10,000 scientists through our network.

NXTECH AS (NORWAY)

NXTECH is an engineering company started in 2008 in Kråkerøy, Norway, that offers design, development and engineering expertise for a variety of electronic products and markets. NXTECH provides in-house resources for project management, electronic design, embedded software engineering and mechanical design. NXTECH offers a professional test-lab with high quality test equipment and experienced personnel for a variety of product qualifications including product quality planning, environmental testing, electromagnetic compatibility testing, quality assurance and improvement, safety and regulations qualifications.

UAB VITTAMED TECHNOLOGIJOS (LITHUANIA)

UAB Vittamed Technologijos is a high-tech company developing non-invasive ultrasonic technologies for measurement and monitoring of key physiological intracranial parameters. The company is based in Kaunas, Lithuania, with office in Connecticut, USA.The aim of the UAB Vittamed Technologijos is technological development of innovative non-invasive technologies and scientific equipment designed for fast and easy physiological monitoring of human brain.

Contacts and Locations:
Eesti Innovatsiooni Instituut OÜ
Sepapaja 6, Ülemiste City, Tallinn 11415 Estonia
Mr. Lauri Nirgi
e-mail: laurinirgi@eiiee
Ms. Madli Kaju
e-mail:  madlikaju@eiiee

Source: DynICP webpage

 

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