Intracranial pressure in patients with sepsis

Authors: D. Pfister, B. Schmidt, P. Smielewski, M. Siegemund, S. P. Strebel, S. Rüegg, S. C. U. Marsch, H. Pargger and L. A. Steiner.

Findings Fifty-two measurements were performed in 16 patients. ICP could be determined in 45 measurements in 15 patients. Seven patients had an ICP>15 mmHg and 11 patients had a CPP<60 mmHg on at least 1 day. We found no significant correlation between ICP and fluid administration, but low CPP was significantly correlated with elevated S-100β (r=−0.47, p=0.001).

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