Projects

TBICare project

TBIcare provides an objective and evidence-based solution for management of TBI by improving diagnostics and treatment decisions for an individual patient by matching a patient’s individual data with the injury’s characteristics. In this way it allows each brain injury patient to receive individual treatment that is optimised for his or her needs.

 

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BrainCare: Scientific research and development of innovative evidence based non-invasive brain diagnostic and monitoring solutions for neurological and TBI patients

BrainCare: Scientific research and development of innovative evidence based non-invasive brain diagnostic and monitoring solutions for neurological and TBI patients. This joint research project runs under Lithuania-Swiss programme "Research and Development". 

The aim of care for patients suffering from brain injury or neurological disease is to provide appropriate patient specific therapeutic interventions based on reliable diagnostic and monitoring data. Key monitoring components involve intracranial pressure (ICP), cerebral perfusion pressure (CPP) and cerebrovascular autoregulation (CVA). ICP is a fundamental neurophysiological parameter because of its importance in intracraniospinal dynamics, its direct effect on cerebral perfusion, and its correlation with prognosis and outcome in head-injury patients.

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Brainsafe II

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The BrainSafe II project aims to develop innovative technology for non-invasive fast-and-easy, accurate and precise absolute intracranial pressure (aICP) diagnostics. The timely application of the device in the diagnosis of TBI patients will save approximately 9.400 lives, reduce the number of permanently disabled citizens by 30.000 and increase the survival rates and lifespan for an additional 136.000 patients with TBI within the EU annually. The innovative aICP measurement device will completely eliminate all the risks associated with invasive methods of ICP diagnostics.

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TBICare : Evidence based Diagnostic and Treatment Planning Solution for Traumatic Brain Injuries

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Traumatic brain injury (TBI) occurs when a sudden trauma causes damage to the brain it is a major health problem and the most common cause of permanent disability in people under the age of 40 years. Yearly cost from TBI in Europe exceeds 100 billion Euros. Recent statistics show a steep increase in the incidence of TBIs, with an increase of 21 % over the last five years threefold greater than the rate of increase in population. Despite this TBI has been seriously underrepresented in medical R&D efforts compared to many other, less significant health problems.

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DynICP project: Innovative Intracranial Pressure and Volume Wave Monitoring System

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The need for a non-invasive ICP measurement technology

An estimated 25M EU citizens suffer from chronic headaches and over 12M have some form of dementia. Each year, between 3M and 4M suffer head injuries (up to 25% of whom require hospitalization), over 1M suffer strokes and over 100,000 suffer various brain tumours. Intracranial pressure (ICP) monitoring is crucial for surveillance of patients with dementia, chronic headache, hydrocephalus, head injury, stroke, brain tumours and other brain diseases as well as for diagnostic purposes to determine the optimum treatment and for monitoring of effects of treatment. However, all currently available options rely on invasive placement of ICP probe in the patient cerebral spinal fluid, thus reducing its use to the intensive care units or hospital wards. Consequently, less than 100,000 patients receive ICP monitoring in the EU each year.

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Proteomics of Brain Trauma-associated Elevated Intracranial Pressure (ICP)

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(This study is currently recruiting participants)

The specific aim of this research is to determine if the blood from brain-injured patients contains reproducible protein markers that appear prior to elevations in intracranial pressure (ICP).

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