Slope of the intracranial pressure waveform after traumatic brain injury

Authors: Franklin D. Westhout, MD, Laura S. Paré, MD, FRCSC, Ralph J. Delfino, MD, PhD, Steven C. Cramer, MD

Published online "Surgical Neurology" 13 February 2008.

Greater systolic ICP waveform slope during inspiration has not been described previously after TBI and is consistent with prior observations in subjects with hydrocephalus. The strong correlation between ICP slope and simultaneous mean ICP suggests that increasing ICP slope might indicate loss of intracranial compliance after TBI. 


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